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The convergence of endosomal and autophagosomal pathways: Implications for APP-CTF degradation

We have reported previously that autophagy is responsible for amyloid precursor protein-C-terminal fragment (APP-CTF) degradation and therefore Aβ clearance. To elucidate the underlying mechanism, using LC3 affinity purification and mass spectrometry analysis, immunoprecipitation (IP), as well as li...

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Detalhes bibliográficos
Main Authors: Tian, Yuan, Chang, Jerry C, Greengard, Paul, Flajolet, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091156/
https://ncbi.nlm.nih.gov/pubmed/24447917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27802
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