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EFFECT OF DORNASE ALFA ON INFLAMMATION AND LUNG FUNCTION: POTENTIAL ROLE IN THE EARLY TREATMENT OF CYSTIC FIBROSIS

Dornase alfa has been shown to reduce markers of inflammation and neutrophil-associated metalloproteinases in cystic fibrosis (CF), suggesting a potential benefit from use of this therapy early in the disease. However, observational studies indicate that dornase alfa is often reserved for “sicker” p...

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Bibliografiske detaljer
Main Authors: Konstan, Michael W., Ratjen, Felix
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090757/
https://ncbi.nlm.nih.gov/pubmed/22093951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2011.10.003
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