Prognostic significance of AMPK activation in advanced stage colorectal cancer treated with chemotherapy plus bevacizumab

BACKGROUND: AMP-activated protein kinase (AMPK) has a central role in cellular energy sensing and is activated in preclinical tumour models following anti-vascular endothelial growth factor (VEGF) therapy. The possible predictive or prognostic role of AMPK status in cancer patients treated with anti...

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Hlavní autoři: Zulato, E, Bergamo, F, De Paoli, A, Griguolo, G, Esposito, G, De Salvo, G L, Mescoli, C, Rugge, M, Nardin, M, Di Grazia, L, Lonardi, S, Indraccolo, S, Zagonel, V
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
Clinical Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090737/
https://ncbi.nlm.nih.gov/pubmed/24892446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.274
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