Low Temperature Condition Prevents Hypoxia-Induced Islet Cell Damage and HMGB1 Release in a Mouse Model

One of the major issues in clinical islet transplantation is the poor efficacy of islet isolation. During pancreas preservation and islet isolation, islets suffer from hypoxia as islets are highly sensitive to hypoxic conditions. Cold preservation has been applied to minimize hypoxia-induced cell da...

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Bibliographic Details
Main Authors: Itoh, Takeshi, Sugimoto, Koji, Takita, Morihito, Shimoda, Masayuki, Chujo, Daisuke, SoRelle, Jeff A., Naziruddin, Bashoo, Levy, Marlon F., Matsumoto, Shinichi
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090700/
https://ncbi.nlm.nih.gov/pubmed/22507397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368912X637514
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