Inhibitory effect of ent-Sauchinone on amyloidogenesis via inhibition of STAT3-mediated NF-κB activation in cultured astrocytes and microglial BV-2 cells

BACKGROUND: ent-Sauchinone is a polyphenolic compound found in plants belonging to the lignan family. ent-Sauchinone has been shown to modulate the expression of inflammatory factors through the nuclear factor-kappa B (NF-κB) signaling pathway. It is well known that neuroinflammation is associated w...

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Autores principales: Song, Suk-Young, Jung, Yu Yeon, Hwang, Chul Ju, Lee, Hee Peom, Sok, Chang Hyun, Kim, Joo Hwan, Lee, Sang Min, Seo, Hyun Ok, Hyun, Byung Kook, Choi, Dong Young, Han, Sang Bae, Ham, Young Wan, Hwang, Bang Yeon, Hong, Jin Tae
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090659/
https://ncbi.nlm.nih.gov/pubmed/24985096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-118
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