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5-Aminosalicylic Acid Inhibits Acute Clostridium difficile Toxin A-Induced Colitis in Rats

We tested the hypothesis that 5-aminosalicylic acid (5-ASA) inhibits toxin A-induced generation of colonic leukotriene B(4) (LTB(4)) and toxin A colitis in rats. Isolated colonic segments in anesthetized rats were treated intraluminally with toxin A for 3 hours with or without 30 minutes of pretreat...

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Detalhes bibliográficos
Autor principal: Vigna, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090440/
https://ncbi.nlm.nih.gov/pubmed/25045574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/389621
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