In Silico Investigation of Traditional Chinese Medicine Compounds to Inhibit Human Histone Deacetylase 2 for Patients with Alzheimer's Disease

Human histone deacetylase 2 (HDAC2) has been identified as being associated with Alzheimer's disease (AD), a neuropathic degenerative disease. In this study, we screen the world's largest Traditional Chinese Medicine (TCM) database for natural compounds that may be useful as lead compounds...

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Autors principals: Hung, Tzu-Chieh, Lee, Wen-Yuan, Chen, Kuen-Bao, Chan, Yueh-Chiu, Lee, Cheng-Chun, Chen, Calvin Yu-Chian
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090436/
https://ncbi.nlm.nih.gov/pubmed/25045700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/769867
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