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A Population Genetic Model for the Initial Spread of Partially Resistant Malaria Parasites under Anti-Malarial Combination Therapy and Weak Intrahost Competition

To develop public-health policies that extend the lifespan of affordable anti-malarial drugs as effective treatment options, it is necessary to understand the evolutionary processes leading to the origin and spread of mutations conferring drug resistance in malarial parasites. We built a population-...

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Detalhes bibliográficos
Main Authors: Kim, Yuseob, Escalante, Ananias A., Schneider, Kristan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090191/
https://ncbi.nlm.nih.gov/pubmed/25007207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101601
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