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Harnessing Gene Expression Networks to Prioritize Candidate Epileptic Encephalopathy Genes

We apply a novel gene expression network analysis to a cohort of 182 recently reported candidate Epileptic Encephalopathy genes to identify those most likely to be true Epileptic Encephalopathy genes. These candidate genes were identified as having single variants of likely pathogenic significance d...

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Detalhes bibliográficos
Main Authors: Oliver, Karen L., Lukic, Vesna, Thorne, Natalie P., Berkovic, Samuel F., Scheffer, Ingrid E., Bahlo, Melanie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090166/
https://ncbi.nlm.nih.gov/pubmed/25014031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102079
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