Epithelial inflammation resulting from an inherited loss-of-function mutation in EGFR

Epidermal growth factor receptor (EGFR) signaling is fundamentally important for tissue homeostasis through EGFR/ligand interactions that stimulate numerous signal transduction pathways. Aberrant EGFR signaling has been reported in inflammatory and malignant diseases but thus far no primary inherite...

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Autores principales: Campbell, Patrick, Morton, Penny, Takeichi, Takuya, Salam, Amr, Roberts, Nerys, Proudfoot, Laura E., Mellerio, Jemima E., Aminu, Kingi, Wellington, Cheryl, Patil, Sachin N., Akiyama, Masashi, Liu, Lu, McMillan, James R., Aristodemou, Sophia, Ishida-Yamamoto, Akemi, Abdul-Wahab, Alya, Petrof, Gabriela, Fong, Kenneth, Harnchoowong, Sarawin, Stone, Kristina, Harper, John I., McLean, W. H. Irwin, Simpson, Michael A., Parsons, Maddy, McGrath, John A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090136/
https://ncbi.nlm.nih.gov/pubmed/24691054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.164
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