Combined NADPH Oxidase 1 and Interleukin 10 Deficiency Induces Chronic Endoplasmic Reticulum Stress and Causes Ulcerative Colitis-Like Disease in Mice

Ulcerative colitis (UC) is a chronic inflammatory bowel disease affecting the rectum which progressively extents. Its etiology remains unknown and the number of treatments available is limited. Studies of UC patients have identified an unbalanced endoplasmic reticulum (ER) stress in the non-inflamed...

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Main Authors: Tréton, Xavier, Pedruzzi, Eric, Guichard, Cécile, Ladeiro, Yannick, Sedghi, Shirin, Vallée, Mélissa, Fernandez, Neike, Bruyère, Emilie, Woerther, Paul-Louis, Ducroc, Robert, Montcuquet, Nicolas, Freund, Jean-Noel, Van Seuningen, Isabelle, Barreau, Frédérick, Marah, Assiya, Hugot, Jean-Pierre, Cazals-Hatem, Dominique, Bouhnik, Yoram, Daniel, Fanny, Ogier-Denis, Eric
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090121/
https://ncbi.nlm.nih.gov/pubmed/25014110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101669
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