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Mutual independence of 5-HT(2) and α1 noradrenergic receptors in mediating deficits in sensorimotor gating

RATIONALE: Prepulse inhibition (PPI), a preattentional information-filtering mechanism, is disrupted by serotonin (5-HT) or norepinephrine (NE) agonists to model deficits seen in schizophrenia, but whether this effect occurs through interactions between these systems is not known. OBJECTIVES: These...

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Detalhes bibliográficos
Main Authors: Baisley, Sarah K., Fallace, Katherine L., Rajbhandari, Abha K., Bakshi, Vaishali P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090044/
https://ncbi.nlm.nih.gov/pubmed/21947334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2490-2
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