A peptide fragment from the human COX3 protein disrupts association of Mycobacterium tuberculosis virulence proteins ESAT-6 and CFP10, inhibits mycobacterial growth and mounts protective immune response

BACKGROUND: Tuberculosis (TB) is one of the most prevalent infectious diseases affecting millions worldwide. The currently available anti-TB drugs and vaccines have proved insufficient to contain this scourge, necessitating an urgent need for identification of novel drug targets and therapeutic stra...

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Detalhes bibliográficos
Main Authors: Samuchiwal, Sachin Kumar, Tousif, Sultan, Singh, Dhiraj Kumar, Kumar, Arun, Ghosh, Anamika, Bhalla, Kuhulika, Prakash, Prem, Kumar, Sushil, Bhattacharyya, Maitree, Moodley, Prashini, Das, Gobardhan, Ranganathan, Anand
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089558/
https://ncbi.nlm.nih.gov/pubmed/24985537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-14-355
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