Rapamycin Attenuated Cardiac Hypertrophy Induced by Isoproterenol and Maintained Energy Homeostasis via Inhibiting NF-κB Activation

Rapamycin, also known as sirolimus, is an immunosuppressant drug used to prevent rejection organ (especially kidney) transplantation. However, little is known about the role of Rapa in cardiac hypertrophy induced by isoproterenol and its underlying mechanism. In this study, Rapa was administrated in...

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Hlavní autoři: Chen, Xi, Zeng, Siyu, Zou, Jian, Chen, Yanfang, Yue, Zhongbao, Gao, Ying, Zhang, Luankun, Cao, Weiwei, Liu, Peiqing
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089551/
https://ncbi.nlm.nih.gov/pubmed/25045214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/868753
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