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Purification, crystallization and preliminary X-ray crystallographic analysis of the UDP-N-acetylmuramoyl-tripeptide-d-alanyl-d-alanine ligase (MurF) from Acinetobacter baumannii

The emergence and global spread of multidrug-resistant Acinetobacter baumannii strains are major threats to public health. Inhibition of peptidoglycan biosynthesis is an effective strategy for the development of antibiotics. The ATP-dependent UDP-N-acetylmuramoyl-tripeptide-d-alanyl-d-alanine ligase...

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Detalhes bibliográficos
Main Authors: An, Young Jun, Jeong, Chang-Sook, Yu, Jeong Hee, Chung, Kyung Min, Cha, Sun-Shin
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089545/
https://ncbi.nlm.nih.gov/pubmed/25005102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14009984
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