A maximum likelihood algorithm for genome mapping of cytogenetic loci from meiotic configuration data.
Frequencies of meiotic configurations in cytogenetic stocks are dependent on chiasma frequencies in segments defined by centromeres, breakpoints, and telomeres. The expectation maximization algorithm is proposed as a general method to perform maximum likelihood estimations of the chiasma frequencies...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1995
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568226/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.21.9824 |
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