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Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction

The transition to puberty and adult fertility both require a minimum level of energy availability. The adipocyte-derived hormone leptin signals the long-term status of peripheral energy stores and serves as a key metabolic messenger to the neuroendocrine reproductive axis. Humans and mice lacking le...

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Main Authors: Bellefontaine, Nicole, Chachlaki, Konstantina, Parkash, Jyoti, Vanacker, Charlotte, Colledge, William, d’Anglemont de Tassigny, Xavier, Garthwaite, John, Bouret, Sebastien G., Prevot, Vincent
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089460/
https://ncbi.nlm.nih.gov/pubmed/24812663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65928
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