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Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease
Recent advances in defining the genetic mechanisms of disease causation and modification in autosomal dominant polycystic kidney disease (ADPKD) have helped to explain some extreme disease manifestations and other phenotypic variability. Studies of the ADPKD proteins, polycystin-1 and -2, and the de...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4089452/ https://ncbi.nlm.nih.gov/pubmed/24892705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72272 |
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