Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication

Damage to the intestinal mucosa results in the translocation of microbes from the intestinal lumen into the circulation. Microbial translocation has been proposed to trigger immune activation, inflammation, and coagulopathy, all of which are key factors that drive HIV disease progression and non-HIV...

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Bibliografiske detaljer
Main Authors: Kristoff, Jan, Haret-Richter, George, Ma, Dongzhu, Ribeiro, Ruy M., Xu, Cuiling, Cornell, Elaine, Stock, Jennifer L., He, Tianyu, Mobley, Adam D., Ross, Samantha, Trichel, Anita, Wilson, Cara, Tracy, Russell, Landay, Alan, Apetrei, Cristian, Pandrea, Ivona
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2014
Fag:
Brief Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089442/
https://ncbi.nlm.nih.gov/pubmed/24837437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75090
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