Signal transduction in T lymphocytes using a conditional allele of Sos.

While Ras activation has been shown to play an important role in signal transduction by the T-lymphocyte antigen receptor, the mechanism of its activation in T cells is unclear. Membrane localization of the guanine nucleotide exchange factor Sos, but not Vav or Dbl, was sufficient for Ras-mediated s...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Holsinger, L J, Spencer, D M, Austin, D J, Schreiber, S L, Crabtree, G R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40892/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568223/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.21.9810
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