Nitric oxide production by polymorphonuclear leucocytes in infected cystic fibrosis sputum consumes oxygen

Chronic Pseudomonas aeruginosa lung infection in cystic fibrosis (CF) patients is characterized by persisting mucoid biofilms in hypoxic endobronchial mucus. These biofilms are surrounded by numerous polymorphonuclear leucocytes (PMNs), which consume a major part of present molecular oxygen (O(2)) d...

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Main Authors: Kolpen, M, Bjarnsholt, T, Moser, C, Hansen, C R, Rickelt, L F, Kühl, M, Hempel, C, Pressler, T, Høiby, N, Jensen, P Ø
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2014
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089181/
https://ncbi.nlm.nih.gov/pubmed/24611476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12318
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