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Directed Bmp4 expression in neural crest cells generates a genetic model for the rare human bony syngnathia birth defect
Congenital bony syngnathia, a rare but severe human birth defect, is characterized by bony fusion of the mandible to the maxilla. However, the genetic mechanisms underlying this birth defect are poorly understood, largely due to limitation of available animal models. Here we present evidence that tr...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4089042/ https://ncbi.nlm.nih.gov/pubmed/24785830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.04.013 |
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