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L-carnitine and PPARα-agonist fenofibrate are involved in the regulation of Carnitine Acetyltransferase (CrAT) mRNA levels in murine liver cells

BACKGROUND: The carnitine acetyltransferase (CrAT) is a mitochondrial matrix protein that directly influences intramitochondrial acetyl-CoA pools. Murine CrAT is encoded by a single gene located in the opposite orientation head to head to the PPP2R4 gene, sharing a very condensed bi-directional prom...

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Autors principals: Kienesberger, Klemens, Pordes, Aniko Ginta, Völk, Thomas Georg, Hofbauer, Reinhold
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089027/
https://ncbi.nlm.nih.gov/pubmed/24962334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-514
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