Aptamer-targeted Antigen Delivery

Effective therapeutic vaccines often require activation of T cell-mediated immunity. Robust T cell activation, including CD8 T cell responses, can be achieved using antibodies or antibody fragments to direct antigens of interest to professional antigen presenting cells. This approach represents an i...

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Detalhes bibliográficos
Main Authors: Wengerter, Brian C, Katakowski, Joseph A, Rosenberg, Jacob M, Park, Chae Gyu, Almo, Steven C, Palliser, Deborah, Levy, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089008/
https://ncbi.nlm.nih.gov/pubmed/24682172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.51
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