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Porcine Nasal Epithelial Cultures for Studies of Cystic Fibrosis Sinusitis

BACKGROUND: Transgenic cystic fibrosis (CF) murine models do not develop spontaneous lung or sinus disease, two major causes of morbidity in human CF patients. Because of these limitations, transgenic CFTR(−/−) pigs have been developed and are currently being characterized. These CF animal models ha...

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Detalhes bibliográficos
Main Authors: Dean, Nichole, Ranganath, Neel K., Jones, Brandon, Zhang, Shaoyan, Skinner, Daniel, Rowe, Steven M., Sorscher, Eric J., Woodworth, Bradford A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4088356/
https://ncbi.nlm.nih.gov/pubmed/24733748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alr.21335
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