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Metergoline inhibits the neuronal Nav1.2 voltage-dependent Na(+) channels expressed in Xenopus oocytes

AIM: Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors. The aim of this study was to investigate the regulatory effects of metergoline on the neuronal Nav1.2 voltage-dependent Na(+) channels in vitro. METHODS: Xenopus oocytes were injected w...

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Detalhes bibliográficos
Main Authors: Lee, Jun-ho, Liu, Jian, Shin, Minkyu, Hong, Moochang, Nah, Seung-yeol, Bae, Hyunsu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4088281/
https://ncbi.nlm.nih.gov/pubmed/24909513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.30
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