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Cooperativity and Equilibrium with FOXA1 Define the Androgen Receptor Transcriptional Program
The pioneering factor FOXA1 opens chromatin to facilitate androgen receptor (AR) binding to prostate-specific genes. How FOXA1 controls the AR cistrome, however, is incompletely understood. Here we show that AR directly binds chromatin through the androgen-response elements (AREs). FOXA1 is not requ...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4088269/ https://ncbi.nlm.nih.gov/pubmed/24875621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4972 |
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