Systemic gene therapy: biodistribution and long-term expression of a transgene in mice.

We have investigated the in vivo efficacy of a systemic gene transfer method, which combines a liposomal delivery system (DLS liposomes) with episomally replicative DNA plasmids to effect long-term expression of a transgene in cells. A single i.v. injection of a plasmid DNA vector containing the luc...

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Main Authors: Thierry, A R, Lunardi-Iskandar, Y, Bryant, J L, Rabinovich, P, Gallo, R C, Mahan, L C
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC40878/
https://ncbi.nlm.nih.gov/pubmed/7568209
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