Genetic vaccination with Flt3-L and GM-CSF as adjuvants: Enhancement of cellular and humoral immune responses that results in protective immunity in a murine model of hepatitis C virus infection

AIM: To investigate whether transfection of plasmid DNA encoding these cytokines enhances both humoral and cellular immune responses to hepatitis C virus (HCV) in a murine model. METHODS: We established a tumor model of HCV infection using syngenic mouse myeloma cells stably transfected with NS5. Co...

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Detalhes bibliográficos
Main Authors: Encke, Jens, Bernardin, Jomo, Geib, Jasmin, Barbakadze, Gocha, Bujdoso, Raymond, Stremmel, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2006
Assuntos:
Viral Hepatitis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087772/
https://ncbi.nlm.nih.gov/pubmed/17131473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i44.7118
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