Mechanism of T cell hyporesponsiveness to HBcAg is associated with regulatory T cells in chronic hepatitis B

AIM: To study the mechanisms of hyporesponsiveness of HBV-specific CD4(+) T cells by testing T(H)1 and T(H)2 commitment and regulatory T cells. METHODS: Nine patients with chronic hepatitis B were enrolled. Peripheral blood mononuclear cells were stimulated with HBcAg or HBsAg to evaluate their pote...

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Autores principales: Kondo, Yasuteru, Kobayashi, Koju, Ueno, Yoshiyuki, Shiina, Masaaki, Niitsuma, Hirofumi, Kanno, Noriatsu, Kobayashi, Tomoo, Shimosegawa, Tooru
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Co., Limited 2006
Materias:
Viral Hepatitis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087740/
https://ncbi.nlm.nih.gov/pubmed/16865771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i27.4310
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