DA-9601, a standardized extract of Artemisia asiatica, blocks TNF-α-induced IL-8 and CCL20 production by inhibiting p38 kinase and NF-κB pathways in human gastric epithelial cells

AIM: To investigate whether, or how, DA-9601, which is a new gastroprotective agent, inhibits TNF-α-induced inflammatory signals in gastric epithelial AGS cells. METHODS: Cell viability was determined by MTT assay. IL-8 and CCL20 promoter activities were determined by a luciferease reporter gene ass...

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Detalhes bibliográficos
Main Authors: Choi, Suck-Chei, Choi, Eun-Ju, Oh, Hyun-Mee, Lee, SungGa, Lee, Jeong-Kun, Lee, Meung-Su, Shin, Yong-Il, Choi, Suck-Jun, Chae, Jeong-Ryong, Lee, Kang-Min, Lee, Won-Jung, Park, Jae-Sik, Shin, Chang-Yell, Oh, Tae-Young, Jun, Chang-Duk
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2006
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087619/
https://ncbi.nlm.nih.gov/pubmed/16937467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i30.4850
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