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Mechanisms of regulation and function of G-protein-coupled receptor kinases
G-protein-coupled receptor kinases (GRKs) interact with the agonist-activated form of G-protein-coupled receptor (GPCR) to affect receptor phosphorylation and to initiate profound impairment of receptor signaling, or desensitization. GPCR forms the largest family of cell surface receptors, and defec...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Baishideng Publishing Group Co., Limited
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4087537/ https://ncbi.nlm.nih.gov/pubmed/17203515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i48.7753 |
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