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Mechanisms of regulation and function of G-protein-coupled receptor kinases

G-protein-coupled receptor kinases (GRKs) interact with the agonist-activated form of G-protein-coupled receptor (GPCR) to affect receptor phosphorylation and to initiate profound impairment of receptor signaling, or desensitization. GPCR forms the largest family of cell surface receptors, and defec...

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Detalhes bibliográficos
Main Authors: Yang, Wen, Xia, Shi-Hai
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087537/
https://ncbi.nlm.nih.gov/pubmed/17203515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i48.7753
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