Alphastatin downregulates vascular endothelial cells sphingosine kinase activity and suppresses tumor growth in nude mice bearing human gastric cancer xenografts

AIM: To investigate whether alphastatin could inhibit human gastric cancer growth and furthermore whether sphingosine kinase (SPK) activity is involved in this process. METHODS: Using migration assay, MTT assay and Matrigel assay, the effect of alphastatin on vascular endothelial cells (ECs) was eva...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Lin, Li, Tao, Li, Rong, Wei, Bo, Peng, Zheng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Baishideng Publishing Group Co., Limited 2006
Gaiak:
Gastric Cancer
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087359/
https://ncbi.nlm.nih.gov/pubmed/16830360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i26.4130
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