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Aging Decreases L-Type Calcium Channel Currents and Pacemaker Firing Fidelity in Substantia Nigra Dopamine Neurons

Substantia nigra dopamine neurons are involved in behavioral processes that include cognition, reward learning, and voluntary movement. Selective deterioration of these neurons is responsible for the motor deficits associated with Parkinson's disease (PD). Aging is the leading risk factor for P...

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Detalhes bibliográficos
Main Authors: Branch, Sarah Y., Sharma, Ramaswamy, Beckstead, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087208/
https://ncbi.nlm.nih.gov/pubmed/25009264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4228-13.2014
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