HER2 Amplification in Gastroesophageal Adenocarcinoma: Correlation of Two Antibodies Using Gastric Cancer Scoring Criteria, H Score, and Digital Image Analysis With Fluorescence In Situ Hybridization

We assessed 103 resected gastroesophageal adenocarcinomas for HER2 amplification by fluorescence in situ hybridization (FISH) and 2 commercial immunohistochemical assays. Of 103, 30 (29%) were FISH-amplified. Both immunohistochemical assays had greater than 95% concordance with FISH. However, as a s...

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Main Authors: Radu, Oana M., Foxwell, Tyler, Cieply, Kathleen, Navina, Sarah, Dacic, Sanja, Nason, Katie S., Davison, Jon M.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086745/
https://ncbi.nlm.nih.gov/pubmed/22431535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1309/AJCPXQVS6YGHPDCY
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