Immunocompetent 3D Model of Human Upper Airway for Disease Modeling and In Vitro Drug Evaluation

[Image: see text] The development of more complex in vitro models for the assessment of novel drugs and chemicals is needed because of the limited biological relevance of animal models to humans as well as ethical considerations. Although some human-cell-based assays exist, they are usually 2D, cons...

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Main Authors: Harrington, Helen, Cato, Paul, Salazar, Fabian, Wilkinson, Malcolm, Knox, Alan, Haycock, John W., Rose, Felicity, Aylott, Jon W., Ghaemmaghami, Amir M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086737/
https://ncbi.nlm.nih.gov/pubmed/24628276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp5000295
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