Neuroprotective effects of volume-regulated anion channel blocker DCPIB on neonatal hypoxic-ischemic injury

AIM: To evaluate the role of swelling-induced activation of volume-regulated anion channels (VRACs) in a neonatal hypoxic-ischemic injury model using the selective VRAC blocker 4-(2-butyl-6,7-dichloro-2-cyclopentyl-indan-1-on5-yl) oxobutyric acid (DCPIB). METHODS: Cerebral hypoxic-ischemic injury wa...

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Detalhes bibliográficos
Main Authors: Alibrahim, Ammar, Zhao, Li-yan, Bae, Christine You-jin, Barszczyk, Andrew, Lf Sun, Christopher, Wang, Guan-lei, Sun, Hong-shuo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086490/
https://ncbi.nlm.nih.gov/pubmed/23202801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.148
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