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Current understanding of TRPM7 pharmacology and drug development for stroke
The initial excitement and countles efforts to find a pharmacological agent that disrupts the excitotoxic pathway of ischemic neuronal death have only led to disappointing clinical trials. Currently, a thrombolytic agent called recombinant tissue plasminogen activator (rt-PA) is the only pharmacolog...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4086489/ https://ncbi.nlm.nih.gov/pubmed/22820907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.94 |
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