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Current understanding of TRPM7 pharmacology and drug development for stroke

The initial excitement and countles efforts to find a pharmacological agent that disrupts the excitotoxic pathway of ischemic neuronal death have only led to disappointing clinical trials. Currently, a thrombolytic agent called recombinant tissue plasminogen activator (rt-PA) is the only pharmacolog...

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Autori principali: Bae, Christine You Jin, Sun, Hong-shuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086489/
https://ncbi.nlm.nih.gov/pubmed/22820907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.94
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