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Bis-aryloxadiazoles as effective activators of the aryl hydrocarbon receptor

Bis -aryloxadiazoles are common scaffolds in medicinal chemistry due to their wide range of biological activities. Previously, we identified a 1,2,4-bis-aryloxadiazole that blocks mammary branching morphogenesis through activation of the aryl hydrocarbon receptor (AHR). In addition to defects in mam...

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Autors principals: Basham, Kaitlin J., Bhonde, Vasudev R., Kieffer, Collin, Mack, James B. C., Hess, Matthew, Welm, Bryan E., Looper, Ryan E.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086406/
https://ncbi.nlm.nih.gov/pubmed/24767852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.04.013
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