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PASTA 2.0: an improved server for protein aggregation prediction

The formation of amyloid aggregates upon protein misfolding is related to several devastating degenerative diseases. The propensities of different protein sequences to aggregate into amyloids, how they are enhanced by pathogenic mutations, the presence of aggregation hot spots stabilizing pathologic...

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Detalhes bibliográficos
Main Authors: Walsh, Ian, Seno, Flavio, Tosatto, Silvio C.E., Trovato, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086119/
https://ncbi.nlm.nih.gov/pubmed/24848016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku399
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