The Role of Complement in Age-Related Macular Degeneration: Heparan Sulphate, a ZIP Code for Complement Factor H?

Age-related macular degeneration (AMD) is the leading cause of blindness in developed nations and has been associated with complement dysregulation in the central retina. The Y402H polymorphism in the complement regulatory protein factor H (CFH) can confer a >5-fold increased risk of developing A...

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Bibliografische gegevens
Hoofdauteurs: Langford-Smith, Alex, Keenan, Tiarnan D.L., Clark, Simon J., Bishop, Paul N., Day, Anthony J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: S. Karger AG 2014
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Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086042/
https://ncbi.nlm.nih.gov/pubmed/24335201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000356513
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