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Compliant 3D Microenvironment Improves β-Cell Cluster Insulin Expression Through Mechanosensing and β-Catenin Signaling

Type 1 diabetes is chronic disease with numerous complications and currently no cure. Tissue engineering strategies have shown promise in providing a therapeutic solution, but maintenance of islet function and survival within these therapies represents a formidable challenge. The islet microenvironm...

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Detalhes bibliográficos
Main Authors: Nyitray, Crystal E., Chavez, Miquella G., Desai, Tejal A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085995/
https://ncbi.nlm.nih.gov/pubmed/24433489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2013.0692
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