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GABAergic Signaling as Therapeutic Target for Autism Spectrum Disorders

γ-Aminobutyric acid (GABA), the main inhibitory neurotransmitter in the adult brain, early in postnatal life exerts a depolarizing and excitatory action. This depends on accumulation of chloride inside the cell via the cation–chloride importer NKCC1, being the expression of the chloride exporter KCC...

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Autors principals: Cellot, Giada, Cherubini, Enrico
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085902/
https://ncbi.nlm.nih.gov/pubmed/25072038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2014.00070
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