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Neuroendocrine-derived peptides promote prostate cancer cell survival through activation of IGF-1R signaling

BACKGROUND: Neuroendocrine (NE) cells promote the progression of prostate cancer to a castration-resistant state through the production of paracrine growth factors. We have demonstrated this principle using in vitro and in vivo proliferative endpoints; however, the contributions of NE-derived pro-su...

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Detalles Bibliográficos
Main Authors: DaSilva, John O., Amorino, George P., Casarez, Eli V., Pemberton, Bradley, Parsons, Sarah J.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085781/
https://ncbi.nlm.nih.gov/pubmed/23192379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22624
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