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Ribosome profiling reveals sequence-independent post-initiation pausing as a signature of translation

The journey of a newly synthesized polypeptide starts in the peptidyltransferase center of the ribosome, from where it traverses the exit tunnel. The interior of the ribosome exit tunnel is neither straight nor smooth. How the ribosome dynamics in vivo is influenced by the exit tunnel is poorly unde...

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Detalhes bibliográficos
Main Authors: Han, Yan, Gao, Xiangwei, Liu, Botao, Wan, Ji, Zhang, Xingqian, Qian, Shu-Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085768/
https://ncbi.nlm.nih.gov/pubmed/24903108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.74
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