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Ribosome profiling reveals sequence-independent post-initiation pausing as a signature of translation
The journey of a newly synthesized polypeptide starts in the peptidyltransferase center of the ribosome, from where it traverses the exit tunnel. The interior of the ribosome exit tunnel is neither straight nor smooth. How the ribosome dynamics in vivo is influenced by the exit tunnel is poorly unde...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4085768/ https://ncbi.nlm.nih.gov/pubmed/24903108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.74 |
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