Chronic intermittent hypobaric hypoxia protects the heart against ischemia/reperfusion injury through upregulation of antioxidant enzymes in adult guinea pigs

AIM: To investigate the protection and the anti-oxidative mechanism afforded by chronic intermittent hypobaric hypoxia (CIHH) against ischemia/reperfusion (I/R) injury in guinea pig hearts. METHODS: Adult male guinea pigs were exposed to CIHH by mimicking a 5000 m high altitude (p(B)=404 mmHg, p(O2)...

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Detalhes bibliográficos
Main Authors: Guo, Hui-cai, Zhang, Zhe, Zhang, Li-nan, Xiong, Chen, Feng, Chen, Liu, Qian, Liu, Xu, Shi, Xiao-lu, Wang, Yong-li
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085733/
https://ncbi.nlm.nih.gov/pubmed/19543301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.57
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