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Transplantable malignant melanoma in LT.B6 congenic mice resembling pigmented epithelioid melanocytoma in humans

Genetically engineered mouse models have been generated to recapitulate major signaling pathways deregulated in melanoma. Although these models are invaluable to delineate the relationship between gene mutations and targeted therapeutics, no spontaneously occurring melanomas are available in laborat...

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Detalhes bibliográficos
Main Authors: Dadras, Soheil S, Silva, Kathleen A., King, Lloyd E., Sundberg, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085667/
https://ncbi.nlm.nih.gov/pubmed/24476622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.47
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