Long non-coding RNA HOTAIR, a c-Myc activated driver of malignancy, negatively regulates miRNA-130a in gallbladder cancer

BACKGROUND: Protein coding genes account for only about 2% of the human genome, whereas the vast majority of transcripts are non-coding RNAs including long non-coding RNAs. A growing volume of literature has proposed that lncRNAs are important players in cancer. HOTAIR was previously shown to be an...

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Autores principales: Ma, Ming-zhe, Li, Chun-xiao, Zhang, Yan, Weng, Ming-zhe, Zhang, Ming-di, Qin, Yi-yu, Gong, Wei, Quan, Zhi-wei
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085645/
https://ncbi.nlm.nih.gov/pubmed/24953832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-156
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