Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation

Angiotensin II (Ang II) is a potent vasopressor peptide that interacts with 2 major receptor isoforms — AT1 and AT2. Although blood pressure is increased in AT2 knockout mice, the underlying mechanisms remain undefined because of the low levels of expression of AT2 in the vasculature. Here we overex...

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Autori principali: Tsutsumi, Yoshiaki, Matsubara, Hiroaki, Masaki, Hiroya, Kurihara, Hiroki, Murasawa, Satoshi, Takai, Shinji, Miyazaki, Mizuo, Nozawa, Yoshihisa, Ozono, Ryoji, Nakagawa, Keigo, Miwa, Takeshi, Kawada, Noritaka, Mori, Yasukiyo, Shibasaki, Yasunobu, Tanaka, Yohko, Fujiyama, Soichiro, Koyama, Yohko, Fujiyama, Atsuko, Takahashi, Hakuo, Iwasaka, Toshiji
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC408562/
https://ncbi.nlm.nih.gov/pubmed/10510333
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