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Preliminary Studies on Validation of Calu-3 Cell Line as a Model for Screening Respiratory Mucosa Irritation and Toxicity

There is need to develop reproducible methods and experimental models for screening mucosal irritation and toxicity for drugs and pharmaceutical excipients. The aim of this study was to validate Calu-3 cell line as a model for screening respiratory irritation and toxicity of drugs and excipients. Ei...

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Bibliographic Details
Main Authors: Ihekwereme, Chibueze, Esimone, Charles, Shao, Di, Agu, Remigius U.
Format: Artigo
Language:Inglês
Published: MDPI 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085599/
https://ncbi.nlm.nih.gov/pubmed/24962675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics6020268
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